Imojev is a live, attenuated vaccine used to prevent Japanese encephalitis (JE).  It is approved for use in individuals aged 9 months and older, typically administered as a single subcutaneous injection.  It is highly effective, though contraindications apply for certain groups.

Dosage and Schedules
• Adults & Children (18+): Administered as a single dose.  In adults, it is generally considered to provide lifelong immunity.
• Children (9 months to under 18 years): Administered as a single dose, but a booster is recommended 1 to 2 years later to provide long-term protection.

Who Should Avoid Imojev
Because Imojev is a live vaccine, it is not safe for certain groups.  Instead, healthcare providers usually recommend an inactivated alternative (such as JEspect).

You should not get Imojev if you are:
• Pregnant or breastfeeding.
• Immunocompromised (e.g., undergoing chemotherapy, high-dose systemic corticosteroids, or have symptomatic HIV).

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JEspect (also known as Ixiaro in some regions) is an inactivated (non-live) vaccine used to protect against Japanese encephalitis, a serious mosquito-borne viral brain infection found in parts of Asia and the Pacific.

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Overview & Eligibility

• How it works: It uses an inactivated virus to help your body build immunity.  Because it is non-live, it is safe for pregnant/breastfeeding women and people who are immunocompromised.

• Who needs it: Recommended for travelers visiting rural or agricultural areas in risk regions during transmission seasons, as well as laboratory workers and those living in endemic regions.

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Dosage Schedule

• Standard Course: Two doses administered 28 days apart via intramuscular injection.

• Accelerated Course: Adults (aged 18+) who are at imminent risk of exposure can get the two doses 7 days apart.

• Boosters: A booster is typically recommended 1 to 2 years later if there is ongoing risk of exposure.

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Common Side Effects

Most side effects are mild and resolve within a few days. They include:

• Pain, redness, or swelling at the injection site

• Fever (more common in children)

• Muscle aches and headaches

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Where to Find & Learn More

• Consult The Australian Immunisation Handbook for detailed clinical guidelines.

• Review the JESPECT Consumer Medicine Information for full product specifications.

• Speak with your local GP, travel clinic, or pharmacy to assess your risk and schedule your vaccination.

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